Neurologically, pleasure comes from specific areas in the brain called hedonic hotspots. “We know of about five” in the human brain, says Kent Berridge, a neuroscientist at the University of Michigan. As Berridge explains for Scientific American (pdf), when hedonic hotspots pick up signals that we’re experiencing something pleasurable, they release their own drug-like neurotransmitters. Nearby receptors pick up these neurotransmitters and create a sensation of liking. Simultaneously, hotspots work with other parts of the brain to coordinate wanting, which is triggered by the neurotransmitter dopamine. Out of that, we develop a conscious understanding that whatever we’re experiencing is pleasurable. Taken together, the system gives us a feeling of enjoyment and deep desire to keep that feeling going, or to get it again in the future.