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Moderna's new cancer vax, AstraZeneca CEO's big pay, and record-high drug shortages: Pharma news round up

Moderna's new cancer vax, AstraZeneca CEO's big pay, and record-high drug shortages: Pharma news round up

Plus, Harrow hikes the price of its eye medication 486%, and Pfizer wants the first FDA approval ever for an RSV vaccine for young adults

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Image for article titled Moderna's new cancer vax, AstraZeneca CEO's big pay, and record-high drug shortages: Pharma news round up
Graphic: Images: George Frey, Brian Snyder, Arnd Wiegmann, aire images

Moderna stock rose after new data suggested that its experimental vaccine could be used to treat a variety of cancers. The American Society of Health-System Pharmacists said the number of ongoing drug shortages has already reached a record in 2024. And Pfizer is hoping to become the first drugmaker to get regulatory approval to expand the allowed use of its RSV vaccine to younger adults.

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Check out those stories and more pharma news highlights.

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A pharmacy technician grabs a bottle of drugs off a shelve
There were 48 new drug shortage in the first three months of 2024.
Image: George Frey (Getty Images)

Four months in, and 2024 has already broken the record for the year with most ongoing drug shortages. As of March 31, the American Society of Health-System Pharmacists (ASHP) has added 48 new drugs to its tracker of national shortages. This brings the number of active shortages in 2024 — so far — to 323, according to a new ASHP report.

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A sign marks the headquarters of Moderna in Cambridge
The company first announced in March 2022 that it was planning to invest $500 million in the Kenyan facility.
Image: Brian Snyder (Reuters)

Moderna said it is pausing its plans to build an mRNA vaccine manufacturing facility in Kenya as demand for mRNA vaccines lags in Africa. The Massachusetts-based vaccine maker says the continent’s uptake of COVID-19 vaccines is no longer sufficient enough to support the project.

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Logo is seen at new factory of Novartis in Stein
Novartis is offering to buy all outstanding shares of MorphoSys for 68 euros ($73) a share.
Image: Arnd Wiegmann (Reuters)

It’s been a busy week for Swiss healthcare giant Novartis. In a series of days, the company said it’s slowing trials of its blockbuster cancer drug and slashing hundreds of jobs — and attempting to snap up a German drugmaker on the side.

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Female ophthalmologist examining male patient in ophthalmology clinic with autorefractometer, examination of eyesight. - stock photo
Harrow bought Triesence, along with four other drugs, from Novartis in 2023 for $130 million.
Image: aire images (Getty Images)

At least 945 brand name drugs have had their list prices hiked in 2024 so far, according to the non-profit 46Brooklyn. One of the largest was Harrow’s eye medication Triesence at a 486% increase to $944 from $161.

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AstraZeneca CEO Pascal Soriot
AstraZeneca CEO Pascal Soriot earned $21.2 million in 2023.
Image: Carlos Osorio (Reuters)

AstraZeneca CEO Pascal Soriot is already one of the highest paid pharmaceutical CEOs in Europe. Still, shareholders of the U.K.-based company can’t agree on whether he deserves a raise or not.

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A sign marks the headquarters of Moderna Therapeutics
Moderna stock grew 6% on Tuesday, closing at $111.60
Image: Brian Snyder (Reuters)

Moderna stock jumped after the the company announced positive results for an experimental, personalized cancer vaccine in an early trial for patients living with a type of head and neck carcinoma.

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View of Pfizer's new respiratory syncytial virus (RSV) vaccine Abrysvo during its manufacture
Pfizer’s RSV vaccine, Abrysvo, generated $515 million in revenue in 2023.
Image: Pfizer (Reuters)

Pharma giant Pfizer said it plans to seek regulatory approval to expand the allowed use of its RSV vaccine, Abrysvo, for adults age 18 to 59, following positive results from a last-stage clinical trial. There is currently no approved vaccine for adults under 59 years old who have an increased risk for the respiratory virus. 

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Ozempic
A study this year found that patients taking semaglutide — the active ingredient in Ozempic— had a lower risk of suicidal thoughts than those who took other diabetes and anti-obesity medications.
Image: George Frey (Reuters)

A European Union regulator will hold a follow-up meeting this week as it reviews anecdotal reports of users of popular diabetes and weight loss drugs — including Novo Nordisk’s Ozempic — saying they experienced suicidal thoughts after starting the medications. 

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